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Article

MicroRNA-22 Is a Key Regulator of Lipid and Metabolic Homeostasis

17 Aug 2023

Abstract excerpt

Obesity is a growing public health problem associated with increased risk of type 2 diabetes, cardiovascular disease, nonalcoholic fatty liver disease (NAFLD) and cancer. Here, we identify microRNA-22 (miR-22) as an essential rheostat involved in the control of lipid and energy homeostasis as well as the onset and maintenance of obesity. We demonstrate through knockout and transgenic mouse models that miR-22...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 37629051
DOI: 10.3390/ijms241612870

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