Article
Retinitis pigmentosa: defined from a molecular point of view.
Survey of ophthalmology - 1 Jan 2000
van Soest S, Westerveld A, de Jong P T, Bleeker-Wagemakers E M, Bergen A A
Abstract excerpt
Retinitis pigmentosa (RP) denotes a group of hereditary retinal dystrophies, characterized by the early onset of night blindness followed by a progressive loss of the visual field. The primary defect underlying RP affects the function of the rod photoreceptor cell, and, subsequently, mostly unknown molecular and cellular mechanisms trigger the apoptotic degeneration of these photoreceptor cells. Retinitis...
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