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Article

Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light‐induced damage

6 Jan 2012

Abstract excerpt

All-trans-retinal and its condensation-products can cause retinal degeneration in a light-dependent manner and contribute to the pathogenesis of human macular diseases such as Stargardt's disease and age-related macular degeneration. Although these toxic retinoid by-products originate from rod and cone photoreceptor cells, the contribution of each cell type to light-induced retinal degeneration is unknown. In...

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PMID: 22220722
DOI: 10.1111/j.1471-4159.2012.07647.x

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