Article

A novel ultra-sensitive method for the detection of FGFR3 mutations in urine of bladder cancer patients – Design of the Urodiag® PCR Kit for surveillance of patients with non-muscle-invasive bladder cancer (NMIBC)

2020-05-18

Abstract excerpt

<title>Abstract</title> <bold>Background </bold>We have recently developed a highly accurate urine-based test, named Urodiag®, associating <italic>FGFR3</italic> mutation and DNA methylation assays for recurrence surveillance in patients with low-, intermediate-, and high-risk NMIBC. Previously, the detection of four <italic>FGFR3</italic> mutations (G372C, R248C, S249C and Y375C) required amplifica...

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Literature Corpus work: 39165dc5-33a4-517f-abbb-c38876df8938
DOI: 10.21203/rs.3.rs-17630/v3

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