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Detection of low frequency FGFR3 mutations in the urine of bladder cancer patients using next-generation deep sequencing

1 Jun 2012

Abstract excerpt

Biological fluid-based noninvasive biomarker assays for monitoring and diagnosing disease are clinically powerful. A major technical hurdle for developing these assays is the requirement of high analytical sensitivity so that biomarkers present at very low levels can be consistently detected. In the case of biological fluid-based cancer diagnostic assays, sensitivities similar to those of tissue-based assays are...

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Share to Bladder and Urothelial Cancer Treatments
Share to Epigenetics and DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24199178
DOI: 10.2147/rru.s32736

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