Article

Dexamethasone-induced <i>PPARG</i> expression in osteogenic differentiation in vitro: impact on <i>SOX9</i> and <i>RUNX2</i> levels

2026-02-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The effects of dexamethasone during in vitro human osteogenesis present a complex picture. On one side, dexamethasone promotes the osteogenic differentiation of human bone marrow mesenchymal stromal cells (BMSCs) by downregulating SOX9 . On the other side, it simultaneously promotes adipogenesis through the upregulation of PPARG . The regulation of SOX9 and PPARG levels...

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Literature Corpus work: 3906c196-b53c-5671-9933-94e4f00253e6
DOI: 10.64898/2026.02.04.703935

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