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The Impact of 3-MA on Autophagy and Atherosclerosis via Wnt/β-catenin and AMPK/mTOR Pathways

2024-03-05

Abstract excerpt

<h4>Objectives: </h4> To study the mechanism of 3-methyladenine (3-MA) regulating autophagy and atherosclerosis (AS). <h4>Methods: </h4> Ox-LDL-treated vascular smooth muscle cells (VSMCs) were used to construct an in vitro model of AS. The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium assay was selected to detect the absorbance (OD) value of VSMCs. WB(Western Blotting) was utilize...

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Literature Corpus work
3903fe9e-6ffa-5cd8-9c5a-515070398eef
DOI
10.21203/rs.3.rs-3999160/v1
Open publication

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