Article

Multiomic Analysis on Human Cell Model of Wolfram Syndrome Reveals Changes In Mitochondrial Morphology And Function

2021-07-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Wolfram syndrome (WFS) is a rare autosomal recessive syndrome in which diabetes mellitus and neurodegenerative disorders occur as a result of wolframin deficiency and increased ER stress. In addition, WFS1 deficiency leads to calcium homeostasis disturbances and can change mitochondrial dynamics. The aim of this study was to evaluate protein levels and changes i...

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Literature Corpus work: a6f50139-68e7-5cda-9ee8-d0b8080b5cc2
DOI: 10.21203/rs.3.rs-675651/v1

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Multiomic Analysis on Human Cell Model of Wolfram Syndrome Reveals Changes In Mitochondrial Morphology And FunctionDOI 10.21203/rs.3.rs-675651/v1Read

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