Article

SARS-CoV-2 NSP13 interacts with TEAD to suppress Hippo-YAP signaling

2023-11-30

Abstract excerpt

The Hippo pathway controls organ development, homeostasis, and regeneration primarily by modulating YAP/TEAD-mediated gene expression. Although emerging studies report Hippo-YAP dysfunction after viral infection, it is largely unknown in the context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we analyzed RNA sequencing data from induced pluripotent stem cell–derived cardiomyocytes (iPSC-...

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Literature Corpus work: 38d1a6da-b35d-5271-b6a3-d8f32f87bfb9
DOI: 10.1101/2023.11.30.569413

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