Article

HCV infection induces ubiquitin-dependent degradation of LATS1, inactivating the Hippo pathway and upregulating transcription of the CYR61 and CTGF genes

2025-04-08

Abstract excerpt

<h4>ABSTRACT</h4> Hepatitis C virus (HCV) is often associated with chronic liver diseases and significant alterations in host cellular signaling. However, the molecular mechanisms underlying HCV- related liver pathogenesis remain to be elucidated. The Hippo signaling pathway, a key regulator of cell proliferation and survival, plays a critical role in maintaining liver homeostasis. Here we investigated the role o...

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Literature Corpus work: 7372b1ee-f48f-5682-be07-5e262ac2955d
DOI: 10.1101/2025.04.08.647823

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HCV infection induces ubiquitin-dependent degradation of LATS1, inactivating the Hippo pathway and upregulating transcription of the CYR61 and CTGF genesDOI 10.1101/2025.04.08.647823Read

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