Article

Single-molecule systems for detection and monitoring of plasma circulating nucleosomes and oncoproteins in Diffuse Midline Glioma

2023-11-21

Abstract excerpt

<h4>Summary</h4> The analysis of cell-free tumor DNA (ctDNA) and proteins in the blood of cancer patients potentiates a new generation of non-invasive diagnostics and treatment monitoring approaches. However, confident detection of these tumor-originating markers is challenging, especially in the context of brain tumors, in which extremely low amounts of these analytes circulate in the patient’s plasma. Here, we...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 38c50907-67b5-5abc-886b-2f0e947104b9
DOI: 10.1101/2023.11.21.568019

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-molecule systems for detection and monitoring of plasma circulating nucleosomes and oncoproteins in Diffuse Midline GliomaDOI 10.1101/2023.11.21.568019Read

Extracellular Histones Profiles of Pediatric H3K27-Altered Diffuse Midline Glioma.Semantic proximity Read

Cross-platform Profiling of ctDNA Using ddPCR: Standardization of the Liquid Biopsy for Pediatric Diffuse Midline GliomaSemantic proximity Read

Standardization of the liquid biopsy for pediatric diffuse midline glioma using ddPCRSemantic proximity Read

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patientsSemantic proximity Read

Electronic DNA Analysis of CSF Cell-free Tumor DNA to Quantify Multi-gene Molecular Response in Pediatric High-grade Glioma.Semantic proximity Read

Liquid biopsy in H3K27M diffuse midline glioma.Semantic proximity Read

Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma.Semantic proximity Read

Clinical utility of a blood based assay for the detection of IDH1.R132H-mutant gliomas.Semantic proximity Read

Liquid biopsy for pediatric diffuse midline glioma: a review of circulating tumor DNA and cerebrospinal fluid tumor DNASemantic proximity Read

Emerging Technologies for Detection of Cell-Free Tumor DNA and RNA in Serum: Towards Early Cancer Detection and MonitoringSemantic proximity Read

Tumor extracellular vesicle RNA profiling predicts treatment response in pediatric diffuse midline gliomaSemantic proximity Read

Molecular Diagnosis of Diffuse Gliomas through Sequencing of Cell-Free Circulating Tumor DNA from Cerebrospinal Fluid.Semantic proximity Read