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The placental protein NRK promotes cell death through its plasma membrane-localizing CNH domain

2023-12-27

Abstract excerpt

Placental development is regulated by the balance between cell proliferation and death. The placental protein NRK (NIK-related kinase) plays a role in preventing excessive placenta growth. We previously demonstrated that NRK underwent rapid molecular evolution in the ancestor of placental mammals and acquired the functional regions, including the phospholipid-binding citron homology (CNH) domain, by which NRK inhi...

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Identifiers and source

Literature Corpus work
38c4f310-bb39-5d46-978f-199f84d22b7e
DOI
10.1101/2023.12.27.573405
Open publication

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The placental protein NRK promotes cell death through its plasma membrane-localizing CNH domainDOI 10.1101/2023.12.27.573405
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