Article

The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication but essential for the production of infectious virus

2020-01-11

Abstract excerpt

The positive stranded RNA genomes of picornaviruses comprise a single large open reading frame flanked by 5′ and 3′ untranslated regions (UTRs). Foot-and-mouth disease virus (FMDV) has an unusually large 5′ UTR (1.3 kb) containing five structural domains. These include the internal ribosome entry site (IRES), which facilitates initiation of translation, and the cis-acting replication element ( cre) . Less well ch...

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Literature Corpus work: 9d74e5a4-28c0-5b65-8c4e-49916340ebe6
DOI: 10.1101/2020.01.10.901801

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