Article
Serratia marcescens Outer Membrane Vesicles rapidly paralyze Drosophila melanogaster through triggering apoptosis in the nervous system
2025-08-25
Abstract excerpt
The pathogenicity of Gram-negative bacteria is mediated by multiple virulence factors that likely include secreted Outer Membrane Vesicles (OMVs) that can act as a cargo for delivery of enzymes or toxins to target tissues. Here, we have studied the effects on the host of OMVs prepared from one of the most potent pathogens of Drosophila melanogaster , Serratia marcescens . OMV injection leads to the apparent demi...
Topics
Open a Topic to create a Post that cites this publication.
- Bacterial Infections and Vaccines
- Biochemical and Structural Characterization
- Cell death mechanisms and regulation
- Insect symbiosis and bacterial influences
- Invertebrate Immune Response Mechanisms
- Mosquito-borne diseases and control
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Pneumonia and Respiratory Infections
Identifiers and source
- Literature Corpus work
- 389b4e07-42d5-5423-adf7-5af17396ef69
- DOI
- 10.1101/2025.08.18.670980