Article
The SKPO-1 peroxidase functions in the hypodermis to protect Caenorhabditis elegans from bacterial infection.
Genetics - 1 Jun 2014
Tiller George R, Garsin Danielle A
Abstract excerpt
In recent years, the synergistic relationship between NADPH oxidase (NOX)/dual oxidase (DUOX) enzymes and peroxidases has received increased attention. Peroxidases utilize NOX/DUOX-generated H2O2 for a myriad of functions including, but not limited to, thyroid hormone biosynthesis, cross-linking extracellular matrices (ECM), and immune defense. We postulated that one or more peroxidases produced by Caenorhabditis...
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