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Sharpening Host Defenses during Infection: Proteases Cut to the Chase

8 Feb 2017

Abstract excerpt

The human immune system consists of an intricate network of tightly controlled pathways, where proteases are essential instigators and executioners at multiple levels. Invading microbial pathogens also encode proteases that have evolved to manipulate and dysregulate host proteins, including host proteases during the course of disease. The identification of pathogen proteases as well as their substrates and...

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Share to Bacterial Infections and Vaccines
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PMID: 28179412
DOI: 10.1074/mcp.o116.066456

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