Article

Machine Learning Prediction of Biomarkers from SNPs and of Disease Risk from Biomarkers in the UK Biobank

2021-04-05

Abstract excerpt

We use UK Biobank data to train predictors for 48 blood and urine markers such as HDL, LDL, lipoprotein A, glycated haemoglobin, … from SNP genotype. For example, our predictor correlates ∼ 0.76 with lipoprotein A level, which is highly heritable and an independent risk factor for heart disease. This may be the most accurate genomic prediction of a quantitative trait that has yet been produced (specifically, for E...

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Literature Corpus work: 38823d3a-9d96-5ad6-bc9d-884dad15cee0
DOI: 10.1101/2021.04.01.21254711

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