Article

A single cell and spatial genomics atlas of human skin fibroblasts in health and disease

2024-12-23

Abstract excerpt

Fibroblasts are critical cells that shape the architecture and cellular ecosystems in multiple tissues. Understanding fibroblast heterogeneity and their spatial context in health and disease has enormous clinical relevance. In this study, we constructed a spatially-resolved atlas of human skin fibroblasts from healthy skin and 23 skin disorders. We define 6 major skin fibroblast populations in health and a further...

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Literature Corpus work: 387a8692-4e5f-5e60-8839-2670ed13ddb0
DOI: 10.1101/2024.12.23.629194

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