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Dermal fibroblast subsets and their roles in inflammatory and autoimmune skin diseases

2 Sept 2025

Abstract excerpt

Fibroblasts are mesenchymal cells that constitute the stroma across tissues. Historically, they have long been perceived as uniform structural cells passively residing in the background during the immune responses within tissues. However, a growing number of recent studies have revealed that fibroblasts are highly heterogeneous and dynamic, responding to various external stimuli with notable plasticity. They...

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PMID: 41038773
DOI: 10.1016/j.jdermsci.2025.08.004

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