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Article

Transcriptional signaling pathways inversely regulated in Alzheimer's disease and glioblastoma multiform

10 Dec 2013

Abstract excerpt

Convincing epidemiological data suggest an inverse association between cancer and neurodegeneration, including Alzheimer's disease (AD). Since both AD and cancer are characterized by abnormal, but opposing cellular behavior, i.e., increased cell death in AD while excessive cell growth occurs in cancer, this motivates us to initiate the study into unraveling the shared genes and cell signaling pathways linking AD...

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PMID: 24322672
DOI: 10.1038/srep03467

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