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Carbapenem Resistance in Acinetobacter baumannii: Mechanisms, Therapeutics, and Innovations

27 Jun 2025

Abstract excerpt

(CRAB) strains poses a critical challenge to healthcare systems due to limited therapeutic options and high mortality rates, especially in intensive care settings. This review explores the epidemiological landscape and molecular mechanisms driving carbapenem resistance, including the production of diverse beta-lactamases (particularly OXA-type enzymes), porin loss, efflux pump overexpression, and mutations in...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 40732008
DOI: 10.3390/microorganisms13071501

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