Article
Characterization of Cefiderocol Heteroresistance in Carbapenem-Resistant Acinetobacter Baumannii (CRAB) Following Exposure to Human Pleural Fluid (HPF)
2023-06-13
Abstract excerpt
<h4>Objectives: </h4> Carbapenem-resistant Acinetobacter baumannii (CRAB) isolates are one of the most difficult pathogens to treat. Cefiderocol, a chlorocatechol-substituted siderophore antibiotic, was approved by the U.S. Food and Drug Administration (FDA) in 2019 indicated for the treatment of infections due to CRAB infections. Despite the initial positive treatment outcomes with this antimicrobial, recent stud...
Topics
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- Advanced biosensing and bioanalysis techniques
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Clostridium difficile and Clostridium perfringens research
- Pharmaceutical and Antibiotic Environmental Impacts
- Plant Pathogenic Bacteria Studies
- Urinary Tract Infections Management
Identifiers and source
- Literature Corpus work
- e4079158-88ea-5b11-ade6-e5858a06a751
- DOI
- 10.20944/preprints202306.0950.v1
