Article

Genome-Wide Association and Population-Tailored Polygenic Risk for Parkinson’s Disease in Taiwan

2026-01-16

Abstract excerpt

Parkinson’s disease genetics remain under-characterized in East Asians. We recruited a Taiwanese case–control cohort (2,245 PD; 2,147 controls), genotyped on the Illumina NeuroBooster Array, and imputed 7.6 million variants using the Taiwan Biobank reference. Logistic-regression GWAS identified genome-wide significant signals at SNCA and MCCC1 ; we also observed suggestive associations at GCH1, PPARGC1A and GA...

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Literature Corpus work: 37c31d3d-b004-5f56-b0f0-bb9626d37117
DOI: 10.64898/2026.01.14.26344088

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