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Progression of the cardiac phenotype of the DE50-MD dog model of Duchenne Muscular Dystrophy, corroborating results of cardiac magnetic resonance imaging with pathology up to 36 months of age

2025-03-06

Abstract excerpt

Cardiomyopathy is an expected consequence of the invariably fatal, X-linked muscle-wasting disease, Duchenne Muscular Dystrophy, (DMD) but onset and progression vary between individuals. Cardiac magnetic resonance imaging (CMR) is invaluable for identification of subclinical myocardial abnormalities, to stratify disease and to identify patients needing early therapeutic intervention. The dystrophin-deficient DE50-...

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Literature Corpus work
379eb719-4c1c-5b0d-bacc-204150054636
DOI
10.1101/2025.02.28.640806
Open publication

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Progression of the cardiac phenotype of the DE50-MD dog model of Duchenne Muscular Dystrophy, corroborating results of cardiac magnetic resonance imaging with pathology up to 36 months of ageDOI 10.1101/2025.02.28.640806
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