Article

An immunochemistry-based screen for chemical inhibitors of DNA-protein interactions and its application to human CGGBP1

2020-10-27

Abstract excerpt

<title>Abstract</title> <p>Background Inhibition of DNA-binding of proteins by small-molecule chemicals holds immense potential in manipulating the activities of DNA-binding proteins. Such a chemical inhibition of DNA-binding of proteins can be used to modulate processes such as replication, transcription, DNA repair and maintenance of epigenetic states. This prospect is currently challenged with the absence of r...

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Literature Corpus work: 376f7206-a5bd-5a9a-bf24-90283b34110d
DOI: 10.21203/rs.2.21430/v4

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