Article

In silico predicted compound targeting the IQGAP1-GRD domain selectively inhibits growth of human acute myeloid leukemia

2023-04-27

Abstract excerpt

<title>Abstract</title> <p>Acute myeloid leukemia (AML) is fatal in majority of adults. Identification of new therapeutic targets and their pharmacologic modulators are needed to improve outcomes. Previous studies had shown that immunization of rabbits with normal peripheral WBCs that had been incubated with fluorodinitrobenzene elicited high titer antibodies that bound to a spectrum of human leukemias. We report...

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Literature Corpus work: 51e0f5ba-36fb-53a3-97b3-f3d04bd37065
DOI: 10.21203/rs.3.rs-2793643/v1

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