Article
[Clinicopathological screening of Lynch syndrome: a report of 2 cases and literature review].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 18 Oct 2015
Si Jing-wen, Wang Li, Ba Xiao-jun, Zhang Xu, Dong Ying, Zhang Ji-xin, Li Wen-ting, Li Ting
Abstract excerpt
Lynch syndrome is an autosomal dominant genetic disease characterized by the early onset of colon cancer, endometrial cancer and other tumors caused by a genetic mutation within DNA mismatch repair (MMR) genes. A small subgroup (approximately 3%-5%) of endometrial cancer and colorectal cancer is related to Lynch syndrome. Identification of these patients in clinical practice will be of great benefit to the...
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