Article

Genome-wide analysis of 944,133 individuals provides insights into the etiology of hemorrhoidal disease

2020-12-04

Abstract excerpt

Hemorrhoidal disease (HEM) affects a large fraction of the population but its etiology including suspected genetic predisposition is poorly understood. We conducted a GWAS meta-analysis of 218,920 HEM patients and 725,213 controls of European ancestry, demonstrating modest heritability and genetic correlation with several other diseases from the gastrointestinal, neuroaffective and cardiovascular domains. HEM poly...

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Literature Corpus work: 3703e9ac-1a6a-5d57-9232-75905e5c1780
DOI: 10.1101/2020.12.03.20242776

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