Article

Long-read whole genome analysis of human single cells

2021-04-13

Abstract excerpt

With long-read sequencing, we have entered an era where individual genomes are routinely assembled to near completion and where complex genetic variation can efficiently be resolved. Here, we demonstrate that long reads can be applied to study the genomic architecture of individual human cells. Clonally expanded CD8+ T-cells from a human donor were used as starting material for a droplet-based multiple displacemen...

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Literature Corpus work: 36b8b5b0-4722-5249-9111-b47d745f5750
DOI: 10.1101/2021.04.13.439527

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