Back to search

Article

Black-necked spitting cobra ( <i>Naja nigricollis)</i> phospholipases A <sub>2</sub> cause <i>Trypanosoma brucei</i> death by blocking endocytosis through the flagellar pocket

2021-11-01

Abstract excerpt

African trypanosomes, such as Trypanosoma brucei, are flagellated protozoa which proliferate in mammals and cause a variety of diseases in people and animals. In a mammalian host, the external face of the African trypanosome plasma membrane is covered by a densely packed coat formed of variant surface glycoprotein (VSG), which counteracts the host adaptive immune response by antigenic variation. The VSG is attach...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
36aae41c-d8a9-5bfd-9fea-a523277a6a22
DOI
10.1101/2021.11.01.466813
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Black-necked spitting cobra ( <i>Naja nigricollis)</i> phospholipases A <sub>2</sub> cause <i>Trypanosoma brucei</i> death by blocking endocytosis through the flagellar pocketDOI 10.1101/2021.11.01.466813
Biogenesis of the Trypanosome Endo-Exocytotic Organelle Is Cytoskeleton MediatedSemantic proximity
To the Surface and Back: Exo- and Endocytic Pathways in Trypanosoma bruceiSemantic proximity
The <i>Trypanosoma brucei</i> Flagellum: Moving Parasites in New DirectionsSemantic proximity
Intrabody induced cell death by targeting the <i>T. brucei</i> cytoskeletal protein <i>Tb</i> BILBO1Semantic proximity
Cell surface localisation of GPI-anchored receptors in <i>Trypanosoma brucei</i>Semantic proximity
Killing of Trypanosoma brucei by concanavalin A: structural basis of resistance in glycosylation mutants.Semantic proximity
Mechanisms of evasion of the African trypanosome : Trypanosoma brucei from the host innate and adaptive immune systemSemantic proximity
Nicastrin-like, a Novel Transmembrane Protein from Trypanosoma cruzi Associated to the Flagellar PocketSemantic proximity
A novel lipase with dual localisation in <i>Trypanosoma brucei</i>Semantic proximity
Adenylate Cyclases of Trypanosoma brucei, Environmental Sensors and Controllers of Host Innate Immune ResponseSemantic proximity
Role for the flagellum attachment zone in the resolution of cell membrane morphogenesis during <i>Leishmania</i> cell divisionSemantic proximity
Modulation of a cytoskeletal calpain-like protein induces major transitions in trypanosome morphology.Semantic proximity
Select a neighboring publication to make it the new centre.