Article

Intrabody induced cell death by targeting the <i>T. brucei</i> cytoskeletal protein <i>Tb</i> BILBO1

2021-07-20

Abstract excerpt

Trypanosoma brucei belongs to a genus of protists that cause life-threatening and economically important diseases of human and animal populations in Sub-Saharan Africa . T. brucei cells are covered in surface glycoproteins some of which are used to escape the host immune system. Exo-/endocytotic trafficking of these and other molecules occurs via a single copy organelle called the flagellar pocket (FP). The FP i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cc5bce05-b08a-5deb-b05a-fab8bc1dc3b1
DOI: 10.1101/2021.07.18.452872

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Intrabody induced cell death by targeting the <i>T. brucei</i> cytoskeletal protein <i>Tb</i> BILBO1DOI 10.1101/2021.07.18.452872Read

Biogenesis of the Trypanosome Endo-Exocytotic Organelle Is Cytoskeleton MediatedSemantic proximity Read

Structural and functional studies of the first tripartite protein complex at the <i>Trypanosoma brucei</i> flagellar pocket collarSemantic proximity Read

Genome-wide subcellular protein localisation in the flagellate parasite <i>Trypanosoma brucei</i>Semantic proximity Read

BILBO1 is a scaffold protein of the flagellar pocket collar in the pathogen Trypanosoma brucei.Semantic proximity Read

Proteomic identification of novel cytoskeletal proteins associated with TbPLK, an essential regulator of cell morphogenesis in<i>Trypanosoma brucei</i>Semantic proximity Read

Architecture of a Host–Parasite Interface: Complex Targeting Mechanisms Revealed Through ProteomicsSemantic proximity Read

The Nucleoporin MLP1 of the nuclear basket is essential for nuclear integrity and ploidy maintenance in <i>Trypanosoma brucei</i>Semantic proximity Read

Genome-wide subcellular protein map for the flagellate parasite Trypanosoma bruceiSemantic proximity Read

The Genome of the African Trypanosome <i>Trypanosoma brucei</i>Semantic proximity Read

<i>Trypanosoma brucei</i> Tim50 Plays a Critical Role in Cell Cycle Regulation and Parasite InfectivitySemantic proximity Read

A luminal proteome of the endoplasmic reticulum and Golgi apparatus reveals a novel modulator of ER stress tolerance in African trypanosomesSemantic proximity Read

Critical role of <i>Babesia bovis</i> spherical body protein 3 in ridge formation on infected red blood cellsSemantic proximity Read