Article

PDIA4: A Novel ER Stress Protein Regulating Hepatic Lipogenesis in Non-Alcoholic Fatty Liver Disease

2023-06-13

Abstract excerpt

Hepatic steatosis is a histological characteristic of non-alcoholic fatty liver disease (NAFLD). Hepatocytes are enriched with the endoplasmic reticulum (ER), essential for lipid metabolism. ER stress modulates lipogenesis and hepatic steatosis in hepatocytes, indicating an involvement of unfolded protein response (UPR) components in the NAFLD pathogenesis. Our previous study demonstrated that serum levels of prot...

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Literature Corpus work: 367d5f03-065f-57b5-a888-c4e752a4ca03
DOI: 10.21203/rs.3.rs-3016609/v1

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