Article

Cross talk between tumor stroma and cancer cells plays a critical role in progressive enrichment of cancer stem cell phenotype in primary breast tumors

2020-06-16

Abstract excerpt

In order to delineate the underlying molecular mechanisms responsible for intra tumoral enrichment of BCSCs in aggressive breast tumors, firstly we evaluated the frequency and characteristics of breast cancer stem cells (BCSCs) within the tumor mass as well as in pathologically normal adjacent tissues in primary breast carcinomas of various clinical and histological grades. Then, we evaluated the expression profil...

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Identifiers and source

Literature Corpus work: 3661293d-ce3b-516b-900b-f3ee960d8d2d
DOI: 10.1101/2020.06.15.152355

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