Article

A tissue specific atlas of gene promoter DNA methylation variability and the clinical value of its assessment

2022-02-08

Abstract excerpt

<h4>Background</h4> Complex diseases have multifactorial etiologies making clinically actionable diagnostic markers difficult to identify. Novel tools with higher diagnostic yield and utility in driving personalized care are needed. <h4>Methods</h4> We utilized Illumina methylation array data from over 2400 samples to assess DNA methylation patterns in 20 distinct cell types ranging from sperm to brain as well a...

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Literature Corpus work: 365423a3-f772-51b4-8e01-290498fb839c
DOI: 10.1101/2022.02.04.479170

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