Article
Synergistic Antileukemic Effects of Hydroxyurea and SRJ23 in T-cell Acute Lymphoblastic Leukemia
2024-12-19
Abstract excerpt
<title>Abstract</title> <p>Background T-cell acute lymphoblastic leukemia (T-ALL) is a highly aggressive blood cancer associated with high relapse rates, affecting about 15% of pediatric and 25% of adult cases. Initial management typically involves hydroxyurea (HU) to reduce elevated white blood cell counts before intensive chemotherapy. However, despite this approach, recurrence remains a substantial challenge,...
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Identifiers and source
- Literature Corpus work
- 35f3b91e-d5e5-50d4-ae8c-16566271ca19
- DOI
- 10.21203/rs.3.rs-5419120/v1
