Article

In Vitro Evaluation of the Potential Synergistic Interactions Between Apigenin and Bortezomib in U266 Multiple Myeloma Cells

2026-02-10

Abstract excerpt

<title>Abstract</title> <p>Purpose This study aimed to evaluate the cytotoxic, apoptotic, and cell cycle regulatory effects of the combination of Apigenin, a natural flavonoid, and the proteasome inhibitor Bortezomib on U266 multiple myeloma cells, and to quantify the potential synergistic interaction. Methods U266 cells were treated with different doses of Bortezomib and Apigenin at 24, 48, and 72 hours of inc...

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Literature Corpus work: 16f0c5c4-f423-5bcb-9806-d763394d7477
DOI: 10.21203/rs.3.rs-8311130/v1

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