Article
Human papillomavirus in head and neck cancer: its role in pathogenesis and clinical implications.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2009
Chung Christine H, Gillison Maura L
Abstract excerpt
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with an annual incidence of approximately 400,000 worldwide. Although the principal risk factors for head and neck cancer remain tobacco and alcohol use, human papillomavirus (HPV) has recently been found to be etiologically associated with 20 to 25% of HNSCC, mostly in the oropharynx. HPV causes human cancers by expressing two viral...
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