Article

In Vivo Production of a Protein via the Delivery of Plasmid DNA by Computationally Designed Polymer Nanoparticles (PNP)

2025-02-19

Abstract excerpt

While monoclonal antibodies (mAbs) are a prominent class of pharmaceutical products there remain significant issues of cost, complexity, and especially delivery: concepts that overcome the need to infuse antibodies frequently are a desirable objective. An attractive approach is to deliver non-integrating DNA directly to muscle tissue, allowing the patient to act as their own so-called “protein factory.” Demonstrat...

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Literature Corpus work: 35acf53f-4f0f-5494-9f4a-dc5b5eb12733
DOI: 10.1101/2025.02.14.638338

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