Article

Retinal affectation in Huntington’s disease mouse models concurs with a local innate immune response

2023-01-19

Abstract excerpt

Huntington’s disease (HD) is a devastating disorder caused by aberrant expansion of CAG repeats in the HTT gene. Striatal dysfunction has been widely studied in HD mouse models. However, cumulative evidence indicates that the retina can also be functionally altered with consequences for visual function and circadian rhythms. The retina is the most exposed part of the central nervous system that can be used for mo...

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Identifiers and source

Literature Corpus work: 3599ed58-e39f-5ba4-aae3-fabb074da10d
DOI: 10.1101/2023.01.17.523578

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