Article
Molecular markers reveal that population structure of the human pathogen Candida albicans exhibits both clonality and recombination.
Proceedings of the National Academy of Sciences of the United States of America - 29 Oct 1996
Gräser Y, Volovsek M, Arrington J, Schönian G, Presber W, Mitchell T G, Vilgalys R
Abstract excerpt
The life history of Candida albicans presents an enigma: this species is thought to be exclusively asexual, yet strains show extensive phenotypic variation. To address the population genetics of C. albicans, we developed a genetic typing method for codominant single-locus markers by screening ran...
Topics
- Candida albicans
- DNA Primers
- DNA, Fungal
- Genetic Markers
- Genetic Variation
- Genotype
- Humans
- Linkage Disequilibrium
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Recombination, Genetic
