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Article

Molecular markers reveal that population structure of the human pathogen Candida albicans exhibits both clonality and recombination.

Proceedings of the National Academy of Sciences of the United States of America - 29 Oct 1996

Gräser Y, Volovsek M, Arrington J, Schönian G, Presber W, Mitchell T G, Vilgalys R

Abstract excerpt

The life history of Candida albicans presents an enigma: this species is thought to be exclusively asexual, yet strains show extensive phenotypic variation. To address the population genetics of C. albicans, we developed a genetic typing method for codominant single-locus markers by screening randomly amplified DNA for single-strand conformation polymorphisms. DNA fragments amplified by arbitrary primers were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8901606
DOI: 10.1073/pnas.93.22.12473
PMCID: PMC38016

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