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Article

Intestinal-epithelial LSD1 controls cytoskeletal-mediated cell identity including goblet cell effector responses required for gut inflammatory and infectious diseases

2020-07-10

Abstract excerpt

<h4>ABSTRACT</h4> Infectious and inflammatory diseases in the intestine remain a serious threat for patients world-wide. Reprogramming of the intestinal epithelium towards a protective effector state is important to manage inflammation and immunity. The role of epigenetic regulatory enzymes within these processes is not yet defined. Here, we use a mouse model that has an intestinal-epithelial specific deletion of...

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Literature Corpus work
355217b9-c476-57d2-99c6-a67a4f2fb211
DOI
10.1101/2020.07.09.186114
Open publication

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Intestinal-epithelial LSD1 controls cytoskeletal-mediated cell identity including goblet cell effector responses required for gut inflammatory and infectious diseasesDOI 10.1101/2020.07.09.186114
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