Article

The Role of Integrin Subunit Alpha 2 (ITGA2) in Pancreatic Cancer Progression

2024-03-15

Abstract excerpt

Background: Pancreatic cancer is a relatively uncommon type of cancer, although it is often very aggressive and highly metastases to other parts of the body. Investigating a potential gene marker or gene targeted therapy can improve the patient’s early prognosis and/or treatment. Objectives: In this study, we identify Integrin Subunit Alpha 2 (ITGA2) as a potential target in inhibiting pancreatic cancer progressio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 34fccd47-474f-5bde-b27a-80aaa4c953e9
DOI: 10.31146/1682-8658-ecg-218-10-120-124

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Role of Integrin Subunit Alpha 2 (ITGA2) in Pancreatic Cancer ProgressionDOI 10.31146/1682-8658-ecg-218-10-120-124Read

The ITGA6-AEBP2 Complex Promotes Transcriptional Activation of GSK3β to Augment Wntβ-Catenin Signaling and Stemness in Pancreatic CancerSemantic proximity Read

Comprehensive Analysis on the Expression and Prognostic value of ITGA Family in Human Pancreatic AdenocarcinomaSemantic proximity Read

High expression ITGA2 affects the expression of MET,PD-L1, CD4 and CD8 with the immune microenvironment in pancreatic cancer patientsSemantic proximity Read

The integrin-extracellular matrix axis in pancreatic cancer.Semantic proximity Read

Transcriptomic analysis reveals high ITGB1 expression as a predictor for poor prognosis of pancreatic cancerSemantic proximity Read

ITGA2 overexpression inhibits DNA repair and confers sensitivity to radiotherapies in pancreatic cancerSemantic proximity Read

CKS2 Predicts A Poor Prognosis and Contributes to Malignant Progression of Pancreatic CancerSemantic proximity Read

Association of RAB5 overexpression in pancreatic cancer with cancer progression and poor prognosis via E-cadherin suppressionSemantic proximity Read

Integrated bioinformatics analysis shows integrin alpha 3 is a prognostic biomarker for pancreatic cancerSemantic proximity Read

Linc00462 promotes pancreatic cancer invasiveness through the miR-665/TGFBR1-TGFBR2/SMAD2/3 pathway.Semantic proximity Read

ITGAX promotes gastric cancer progression via epithelial-mesenchymal transition pathwaySemantic proximity Read

β1 and β3 integrins in breast, prostate and pancreatic cancer: A novel implication (Review)Semantic proximity Read