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Article

Linc00462 promotes pancreatic cancer invasiveness through the miR-665/TGFBR1-TGFBR2/SMAD2/3 pathway.

Cell death & disease - 13 Jun 2018

Zhou Bin, Guo Weidong, Sun Chuandong, Zhang Bingyuan, Zheng Fang

Abstract excerpt

Emerging evidence has identified that long non-coding RNAs (lncRNAs) may play an important role in the pathogenesis of many cancers, pancreatic cancer (PC) included. However, the role of linc00462 in PC remains unclear. The aim of our present study was to investigate the potential functions of linc00462 in PC and to identify the underlying mechanisms of action. CCK8 assay, transwell assay, cell cycle assay, cell...

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Topics

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Share to Cell Adhesion
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Transforming Growth Factor-beta Type I

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Source

Open in PubMed Open full text

Identifiers

PMID: 29899418
DOI: 10.1038/s41419-018-0724-5
PMCID: PMC5999603

Genes

TGFBR1
SMAD2
TGFBR2
OSM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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