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Article

β1 and β3 integrins in breast, prostate and pancreatic cancer: A novel implication (Review)

16 Feb 2018

Abstract excerpt

Integrins are transmembrane glycoproteins that consist of an α and a β subunit. Specific integrin heterodimers preferentially bind to distinct extracellular matrix (ECM) proteins to affect the characteristics of cells or the components of the ECM. Among the different integrins, β1 and β3 integrins serve essential roles in the progression of different cancer-associated processes, including the initiation,...

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PMID: 29556293
DOI: 10.3892/ol.2018.8076

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