Article

Recessive and sex-dependent genetic effects in primary hypertension

2022-06-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Essential hypertension is a polygenic disease that affects almost half of the adult population in the USA. It is a major risk factor for renal, cerebrovascular, and cardiovascular diseases. Previous studies used UK-Biobank (UKB) GWAS results for hypertension to create a polygenic risk score (PRS), with the top and bottom 5% of the PRS translating to a 4-fold difference in the...

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Literature Corpus work: 34ebd68e-f349-56f8-b539-5a7104c7c56b
DOI: 10.1101/2022.05.31.22275828

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