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Article

Gene-based association study reveals a distinct female genetic signal in primary hypertension.

Human genetics - 1 Jul 2023

Zucker Roei, Kovalerchik Michael, Linial Michal

Abstract excerpt

Hypertension is a polygenic disease that affects over 1.2 billion adults aged 30-79 worldwide. It is a major risk factor for renal, cerebrovascular, and cardiovascular diseases. The heritability of hypertension is estimated to be high; nevertheless, our understanding of its underlying mechanisms remains scarce and incomplete. This study covered the entries from European ancestry from the UK-Biobank (UKB), with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37133573
DOI: 10.1007/s00439-023-02567-9

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