Article
Exploring hypertension genome-wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics.
Wiley interdisciplinary reviews. Systems biology and medicine - 1 Jan 2000
Cabrera Claudia P, Ng Fu Liang, Warren Helen R, Barnes Michael R, Munroe Patricia B, Caulfield Mark J
Abstract excerpt
UNLABELLED: Hypertension is a major risk factor for global mortality. Recent genome-wide association studies (GWAS) have led to successful identification of many genetic loci influencing blood pressure, although these studies account for less than 5% of heritability. While genetic discovery efforts continue, it is timely to pause and reflect on what information has been gained to date from reported loci....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.