Article

Constitutive Activation of STAT3 in Myeloma Cells Cultured in a Three-Dimensional, Reconstructed Bone Marrow Model

2018-06-08

Abstract excerpt

Malignant cells cultured in three-dimensional (3D) models have been found to be phenotypically and biochemically different from their counterparts cultured conventionally. Since most of these studies employed solid tumor types, how 3D culture affects multiple myeloma (MM) cells is not well understood. Here, we compared MM cells (U266 and RPMI8226) in a 3D culture model with those in conventional culture. While the...

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Literature Corpus work: 34dec7a7-c0d6-5b9b-84b4-badf0a9c0a4e
DOI: 10.20944/preprints201803.0151.v2

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