Article

TRIM3 exacerbates chondrocyte apoptosis through suppression of AKT/mTOR signaling pathway in osteoarthritis

2025-10-20

Abstract excerpt

<title>Abstract</title> <p>Introduction: Osteoarthritis (OA), a prevalent cause of global disability, is characterized by progressive articular cartilage degeneration. Despite its clinical significance, the molecular pathogenesis remains incompletely understood, posing challenges for developing disease-modifying therapies. <h4>Methods:</h4> Utilizing knee OA datasets from GEO database, we systematically evaluated...

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Literature Corpus work: 34b59c53-2e84-556c-8f8a-42fdf093975b
DOI: 10.21203/rs.3.rs-7739549/v1

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