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Article

High TRB3 expression induces chondrocyte autophagy and senescence in osteoarthritis cartilage

1 Jul 2022

Abstract excerpt

Objective: Osteoarthritis is closely related to aging. Tribbles homologue 3 (TRB3) is found to display age-related expression and contributes to the regulation of cell proliferation, differentiation and fibrosis. In this study, we aimed to investigate the potential involvement of TRB3 in cartilage autophagy and aging in osteoarthritis. Methods: Cartilage tissue samples were collected from osteoarthritis patients...

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Share to Autophagy in Disease and Therapy
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PMID: 35776529
DOI: 10.18632/aging.204066

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